Molecular Rotors for the Detection of Chemical Warfare Agent Simulants

作者:Kim Tae Il; Maity Shubhra Bikash; Bouffard Jean; Kim Youngmi
来源:Analytical Chemistry, 2016, 88(18): 9259-9263.
DOI:10.1021/acs.analchem.6b02516

摘要

The fluorogenic probe o-OH is able to detect and quantify orgariop-hosphoms nerve agent mimics in solution and in the vapor phase following immobilization on a solid substrate, making the system a suitable candidate for the field detection of chemical warfare agents. Detection is achieved by the suppression of internal rotation upon phosphorylation of a reactive phenolate, resulting in a large fluorescence "turn-on" response.

  • 出版日期2016-9-20