Direct arylation of heterocycles through C-H bond cleavage using metal-organic-framework Cu-2(OBA)(2)( BPY) as an efficient heterogeneous catalyst

作者：Thanh Truong; Nguyen Vu T; Le Hue T X; Phan Nam T S^*

来源：RSC Advances, 2014, 4(94): 52307-52315.

DOI：10.1039/c4ra09092f

A crystalline porous metal-organic-framework Cu-2(OBA)(2)(BPY) was synthesized and characterized by X-ray powder diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), thermogravimetric analysis (TGA), Fourier transform infrared (FT-IR), atomic absorption spectrophotometry (AAS), and nitrogen physisorption measurements. The Cu-MOF was shown to be an efficient heterogeneous catalyst for direct C-arylation of a variety of heterocycles by iodoarenes. The optimal conditions employed tBuOLi in dioxane at elevated temperature. In addition, a leaching test was also conducted to investigate the heterogeneity. Gratifyingly, the MOF catalyst can be facilely recycled several times under identical conditions without remarkable loss in catalytic reactivity.

• 出版日期2014