Association Between Nonalcoholic Fatty Liver Disease and Coronary Artery Disease Complexity in Patients With Acute Coronary Syndrome: A Pilot Study

作者：Agac Mustafa Tarik^*; Korkmaz Levent; Cavusoglu Goekhan; Karadeniz Ayse Gul; Agac Suret; Bektas Huseyin; Erkan Hakan; Varol Mustafa Oguz; Vatan Mehmet Bulent; Acar Zeydin; Mentese Umit; Celik Sukrue

来源：Angiology, 2013, 64(8): 604-608.

DOI：10.1177/0003319713479155

• nonalcoholic fatty liver disease
• SYNTAX score
• acute coronary syndrome

Nonalcoholic fatty liver disease (NAFLD) is highly prevalent in patients with acute coronary syndrome (ACS). We assessed the association between NAFLD and SYNTAX Score (SS) in patients with ACS. Eighty consecutive patients with ACS were enrolled. Patients were evaluated using ultrasound to detect NAFLD and hepatosteatosis stage. The prevalence of NAFLD was 81.2%; median SS was 15. The SS was significantly higher in patients with NAFLD (18 +/- 8 vs. 11 +/- 5, P = .001). Univariate analysis showed that the stage of NAFLD correlated with SS (r = .6, P < .001). In multivariate binary logistic analysis, increased age (odds ratio [OR], 1.05; 95% confidence interval [CI],1.00-1.10) and presence of NAFLD (OR, 13.20; 95% CI, 2.52-69.15) were independent factors associated with supramedian SS. In conclusion, among patients with ACS, those with NAFLD have more complex CAD as assessed by SS.

• 出版日期2013-11