Adverse drug reactions among patients admitted with infectious diseases at a Brazilian hospital

作者：Saavedra Pamela Alejandra; Milward de Azevedo Meiners Micheline Marie; Lopes Luciane Cruz; da Silva Emilia Vitria; Mendonca da Silva Dayde Lane; Noronha Elza Ferreira; de Toledo Maria Ines^*

来源：Revista da Sociedade Brasileira de Medicina Tropical, 2016, 49(6): 763-767.

DOI：10.1590/0037-8682-0238-2016

• Adverse drug reactions
• Pharmacovigilance
• Hospitals

Introduction: Despite the therapeutic benefits of drugs, adverse drug reactions (ADRs) occur. Method: We assessed a series of suspected ADRs identified from notifications and intensive monitoring of inpatients from March 2013 to March 2014. Results: Skin reactions predominated (31%). Systemic anti-infective agents were implicated in 16 (72%) reactions. Fifteen (68%) ADRs were classified as possible. The implicated drug was not correctly identified by the healthcare team in 12 cases. Conclusions: Some reactions were not correctly attributed to the causative drug(s), suggesting that the use of a validated evaluation method can promote successful identification of causal links between ADRs and drugs.

• 出版日期2016-12