Nucleus to Mitochondria: Lost in Transcription, Found in Translation

作者:St Pierre Julie*; Topisirovic Ivan*
来源:Developmental Cell, 2016, 37(6): 490-492.
DOI:10.1016/j.devcel.2016.06.003

摘要

Mitochondrial genes reside in the nucleus and mitochondria. In a recent paper in Nature, Couvillion et al. (2016) describe their development of a "mitoribosome profiling" approach and demonstrate that changes in expression of nuclear- and mitochondrial-encoded genes are coordinated at the level of translation during metabolic adaptation to fuel source changes.

  • 出版日期2016-6-20
  • 单位McGill