Phytochemical and antimicrobial investigation of latex from Euphorbia abyssinica Gmel.

作者：El Fiky Fathy^*; Asres Kaleab; Gibbons Simon; Hammoda Hala; Badr Jihau; Umer Shemsu

来源：Natural Product Communications, 2008, 3(9): 1505-1508.

DOI：10.1177/1934578x0800300922

• Euphorbia abyssinica Gmel.
• Euphorbiaceae
• 8(R)-hydroxy-dec-3(E)-en-oic acid
• antimicrobial activity

Phytochemical investigation of the latex of Euphorbia abyssinica Gmel (Euphorbiaceae) afforded a new hydroxy unsaturated fatty acid, 8(R)-hydroxy-dec-3(E)-en-oic acid (1), in addition to the four known compounds lupeol (2), beta-sitosterol (3), oleanolic acid (4) and beta-sitosterol-3-O-glucoside (5). The in vitro antibacterial and antifungal activities of the isolated compounds, as well as the total methanol extract, were studied against different micro-organisms; compound 1 displayed reasonable antifungal activities towards the tested fungi.

• 出版日期2008