A New Sydonic Acid Derivative From a Marine Derived-Fungus Aspergillus sydowii

作者:Xu, Xiuli*; Zhao, Shujiang; Yin, Liyuan; Yu, Ying; Chen, Zhengkun; Shen, Huihui; Zhou, Li
来源:Chemistry of Natural Compounds, 2017, 53(6): 1056-1058.
DOI:10.1007/s10600-017-2200-3

摘要

Methyl (3-hydroxy-4-(2-hydroxy-6-methylheptan-2-yl)benzoyl)glycinate (1), a new sydonic acid derivative with glycinate, together with sydonic acid (2), sydowic acid (3), and 7-deoxy-7,14-didehydrosydonic acid (4), were isolated from a marine-derived Aspergillus sydowii strain CUGB-F126. Their structures were elucidated by spectroscopic analysis, including high-resolution mass spectroscopy, and 1D and 2D NMR techniques. All of these compounds did not show inhibitory activity against Staphylococcus aureus and Candida albicans.