科研之友
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摘要
An efficient approach towards peptide synthesis that allows easy access to variety of small peptides via one-pot aziridine-mediated ligation/desulfurization strategy has been described. The protocol afforded a library of phenylalanine- and tryptophan-containing alpha-peptides in good yields by regioselective ring-opening of aziridine-3aryl-2-carboxylates with peptide thioacids, followed by desulfurization.
- 出版日期2017-8-4
