Antimelanogenic and antioxidative properties of Bifidobacterium bifidum

作者：Huang Huey Chun; Huang Wen Ying; Chiu Shao Hua; Ke Hui Ju; Chiu Shu wen; Wu Sze Yun; Kuo Feng Sheng; Chang Tsong Min^*

来源：Archives of Dermatological Research, 2011, 303(7): 527-531.

DOI：10.1007/s00403-011-1135-y

• Bifidobacterium bifidum
• Tyrosinase
• Melanin
• Antioxidant

Various skin hyperpigmentation disorders consist in accumulation and overproduction of melanin. In this report, we investigated the melanogenesis inhibitory and antioxidant effects of Bifidobacterium bifidum culture filtrate. The results revealed that B. bifidum culture filtrate effectively suppresses murine tyrosinase activity and decreases the amount of intracellular melanin in a dose-dependent manner. Additionally, the bacterial culture filtrate-scavenged DPPH and ABTS radicals, and shows potent-reducing power in a dose-dependent pattern. Our results expand the application of B. bifidum culture filtrate in the development and research of skin-whitening ingredients.

• 出版日期2011-9
• 单位中国医科大学