Ultrafast 3D balanced steady-state free precession MRI of the lung: Assessment of anatomic details in comparison to low-dose CT

作者：Heye Tobias^*; Sommer Gregor; Miedinger David; Bremerich Jens; Bieri Oliver

来源：Journal of Magnetic Resonance Imaging, 2015, 42(3): 602-609.

DOI：10.1002/jmri.24836

• MRI
• CT
• chest
• anatomical details
• pulmonary nodules

PurposeTo evaluate the anatomical details offered by a new single breath-hold ultrafast 3D balanced steady-state free precession (uf-bSSFP) sequence in comparison to low-dose chest computed tomography (CT).
Materials and MethodsThis was an Institutional Review Board (IRB)-approved, Health Insurance Portability and Accountability Act (HIPAA)-compliant prospective study. A total of 20 consecutive patients enrolled in a lung cancer screening trial underwent same-day low-dose chest CT and 1.5T MRI. The presence of pulmonary nodules and anatomical details on 1.9 mm isotropic uf-bSSFP images was compared to 2 mm lung window reconstructions by two readers. The number of branching points on six predefined pulmonary arteries and the distance between the most peripheral visible vessel segment to the pleural surface on thin slices and 50 mm maximum intensity projections (MIP) were assessed. Image quality and sharpness of the pulmonary vasculature were rated on a 5-point scale.
ResultsThe uf-bSSFP detection rate of pulmonary nodules (32 nodules visible on CT and MRI, median diameter 3.9 mm) was 45.5% with 21 false-positive findings (pooled data of both readers). Uf-bSSFP detected 71.2% of branching points visible on CT data. The mean distance between peripheral vasculature and pleural surface was 13.04.2 mm (MRI) versus 8.5 +/- 3.3 mm (CT) on thin slices and 8.6 +/- 3.9 mm (MRI) versus 4.6 +/- 2.5 mm (CT) on MIPs. Median image quality and sharpness were rated 4 each.
ConclusionAlthough CT is superior to MRI, uf-bSSFP imaging provides good anatomical details with sufficient image quality and sharpness obtainable in a single breath-hold covering the entire chest. J. Magn. Reson. Imaging 2015;42:602-609.

• 出版日期2015-9