A synthesis of functionalized spiro isobenzofuran-1,6 '-[1,3] thiazines from phthalic anhydride-malononitrile adduct and ammonium carbamodithioates

作者：Diyanatizadeh Mohammad Hadi; Yavari Issa^*

来源：Journal of Sulfur Chemistry, 2016, 37(1): 54-60.

DOI：10.1080/17415993.2015.1089439

• Spiro heterocycles
• isobenzofuran
• 1
• 3-thiazine
• S-nucleophiles
• carbamodithioates

The reaction of 2-[3-oxo-isobenzofuran-1(3H)-ylidene]malononitrile, generated from phthalic anhydride and malononitrile, with ammonium alky(aryl)carbamodithioates, leading to the formation of functionalized spiro isobenzofuran-1,6'-[1,3] thiazine systems, in good yields, is reported.
[GRAPHICS]
Highlights The reaction of 2-[3-oxo-isobenzofuran-1(3H)-ylidene]malononi trile, with ammonium alky(aryl)carbamodithioates, leads to the formation of functionalized spiro isobenzofuran-1,6'-[1,3]thiazine systems, in good yields.

• 出版日期2016