A BIOMECHANICAL COMPARISON OF BLOOD FLOW AND MECHANICAL CHARACTERISTICS OF THE EARLY ARTERIOSCLEROTIC AND HEALTHY ARTERIES USING A FLUID-WALL INTERACTION MODEL

作者：Fan, He

来源：Biomedical Engineering - Applications, Basis and Communications, 2014, 26(02): 1450028.

DOI：10.4015/s1016237214500288

<jats:p> A fluid-wall interaction model was introduced to investigate and compare the properties of blood flow, wall stress and deformation of the early arteriosclerotic and healthy arteries. The unsteady blood flow was assumed to be laminar, Newtonian, viscous and incompressible. The vessel wall was assumed to be linear-elastic, isotropic and incompressible. The fluid-wall interaction algorithm was constructed using a finite element method. The results show that the blood flow, wall stress and strain distributions of both arteries are similar. The blood flow characteristics of the diseased artery are similar to those of the healthy artery, which may be the main reason that the early arteriosclerosis could be reversible and treated by itself. The values of velocities, wall shear stresses, pressures and wall stresses of the diseased artery are approximately equal to those of the healthy artery, however the values of wall strains of both arteries are different and the cyclic strain ratio of the diseased artery is higher than that of the healthy artery. A high cyclic strain ratio is thought to be disadvantageous for arterial tissue. A new parameter anti-fatigue index (AFI) is introduced to evaluate mechanical fatigue of artery in the study. AFI is effective in characterizing the anti-fatigue ability of artery. </jats:p>

• 出版日期2014-4
• 单位北京大学