Feasibility of bone assessment by using the nonlinear parameter in trabecular bone

作者：Lee Kang Il^*

来源：Journal of the Korean Physical Society, 2013, 62(8): 1108-1113.

DOI：10.3938/jkps.62.1108

• Osteoporosis
• Trabecular bone
• Bone density
• Quantitative ultrasound
• Speed of sound
• Normalized broadband ultrasound attenuation
• Nonlinear parameter B/A

The purpose of the present study is to investigate the feasibility of assessing bone status and osteoporosis by using the nonlinear parameter B/A in bovine trabecular bone in vitro. The B/A values measured in 18 bovine femoral trabecular bone samples by using a finite-amplitude through-transmission method ranged from 63.3 to 122.6. The apparent bone density was highly correlated with the B/A and with the existing quantitative ultrasound parameters of the speed of sound (SOS) and the normalized broadband ultrasound attenuation (nBUA), with Pearson%26apos;s correlation coefficients of r = 0.83 to 0.96. The best univariate predictor of the apparent bone density was the B/A, with an adjusted squared correlation coefficient of r (2) = 0.91. These results suggest that the B/A, in addition to the SOS and the nBUA, may have potential as an index for the assessment of bone status and osteoporosis.

• 出版日期2013-4