科研之友
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摘要
PURPOSE: To analyze the accuracy and consistency of corneal flap thickness created in myopic LASIK using the Mona One Use-Plus microkeratome compared with the Mona M2 Single Use 90-mu m microkeratome. METHODS: Bilateral LASIK was performed in 68 myopic patients. Flaps were created using the One Use-Plus microkeratome in 82 eyes (41 patients) and the M2 90-mu m microkeratome in 54 eyes (27 patients). Flap complications and visual outcomes were evaluated. Horizontal "High Res. Corneal" scan pattern of anterior segment optical coherence tomography (AS-OCT) was applied to measure flap thickness at five locations (0, /- 2, and /- 3.5 mm from the corneal vertex) on the first postoperative day. RESULTS: No significant differences were noted in flap complications and visual outcomes between groups. The central flap thickness was dramatically thinner in the One Use-Plus group (114.7 /- 10.1 mu m and 109.4 /- 11.0 mu m for right and left eyes, respectively) than in the M2 group (155.6 /- 14.8 mu m and 151.6 /- 12.5 mu m for right and left eyes, respectively) (P<.001) The One Use-Plus did not show a markedly better uniformity than the M2; the variation was mainly observed in the periphery. Multiple linear regression showed that for the One Use-Plus, the steeper the preoperative keratometry, the thicker the flap thickness, and for the M2, the thicker the preoperative pachymetry, the thicker the flap (P<.1). CONCLUSIONS: The One Use-Plus and M2 microkeratomes have similar safety and efficacy. The flap created by the One Use-Plus was much thinner than the flap created with the M2; however, the One Use-Plus can not realize a fully planar-shaped flap. [J Refract Surg. 2010;26(6):403-410.] doi:10.3928/1081597X-20090710-04
- 出版日期2010-6
- 单位北京大学
