A comparison of the effects of intrathecal ropivacaine and bupivacaine during cesarean section

作者：Eryilmaz Nuray Camgoz; Gunaydin Berrin^*

来源：Turkish Journal of Medical Sciences, 2011, 41(2): 219-226.

DOI：10.3906/sag-1008-994

• Surgery
• Cesarean section
• anesthetic technique
• spinal
• local anesthetics
• bupivacaine
• ropivacaine

Aim: To compare the effects of intrathecal plain bupivacaine or ropivacaine with those of opioids on sensory and motor block characteristics during cesarean section (C/S).
Materials and methods: Fifty-two ASA I or II women were randomly allocated into 2 groups to administer either 10 mg of 0.5% plain bupivacaine (Group B), or 15 mg of 0.75% plain ropivacaine (Group R) with 25 mu g fentanyl and 100 mu g morphine for spinal anesthesia. Characteristics of the sensory and motor block were recorded.
Results: The time to achieve sensory block at T(6) was significantly faster in Group B than in Group R (2.7 +/- 1.8 min vs. 4.2 +/- 2.5 min). The time to reach maximum sensory block was significantly faster in Group B than in Group R (8.1 +/- 4.1 min vs. 11.6 +/- 5.6 min). The times of sensory block regression to T(10) and L(1) dermatomes were significantly shorter in Group B (118.2 +/- 24.2 min and 145.5 +/- 28.1 min, respectively) than in Group R (135 +/- 32.1 min and 162.5 +/- 32.5 min, respectively). Motor block duration was significantly longer in Group B than in Group R (165.8 +/- 32.5 min vs. 135.2 +/- 45.7 min).
Conclusion: Intrathecal plain ropivacaine with opioids might be superior to bupivacaine in terms of a longer sensory block, and a shorter motor block duration for C/S.

• 出版日期2011-4