A nonlinear delayed model for the immune response in the presence of viral mutation

作者：Messias D; Gleria Iram; Albuquerque S S; Canabarro Askery^*; Stanley H E

来源：Physica A: Statistical Mechanics and Its Applications , 2018, 492: 215-221.

DOI：10.1016/j.physa.2017.09.088

• Delay differential equations
• Immune response
• Non-instantaneous systems

We consider a delayed nonlinear model of the dynamics of the immune system against a viral infection that contains a wild-type virus and a mutant. We consider the finite response time of the immune system and find sustained oscillatory behavior as well as chaotic behavior triggered by the presence of delays. We present a numeric analysis and some analytical results.

• 出版日期2018-2-15