A novel acid-catalyzed C5-alkylation of oxindoles using alcohols

作者:Reddy Chada Raji*; Jithender Enukonda; Krishna Gaddam; Reddy Gunreddy Venkat; Jagadeesh Bharatam
来源:Organic and Biomolecular Chemistry, 2011, 9(10): 3940-3947.
DOI:10.1039/c0ob01144d

摘要

A novel C5-alkylation of oxindoles using alcohols as alkylating agents under acid catalysis is described for the first time. The reactions of various benzylic, allylic and propargylic alcohols are studied to obtain the corresponding 5-substituted oxindoles in good yields.

  • 出版日期2011