Alpha shape and Delaunay triangulation in studies of protein-related interactions

作者：Zhou, Weiqiang^*; Yan, Hong

来源：Briefings in Bioinformatics, 2014, 15(1): 54-64.

DOI：10.1093/bib/bbs077

• Delaunay triangulation
• alpha shape
• protein-DNA interactions
• protein-protein interactions
• protein-ligand interactions
• protein structure analysis

In recent years, more 3D protein structures have become available, which has made the analysis of large molecular structures much easier. There is a strong demand for geometric models for the study of protein-related interactions. Alpha shape and Delaunay triangulation are powerful tools to represent protein structures and have advantages in characterizing the surface curvature and atom contacts. This review presents state-of-the-art applications of alpha shape and Delaunay triangulation in the studies on protein-DNA, protein-protein, protein-ligand interactions and protein structure analysis.

• 出版日期2014-1
• 单位香港城市大学