Assessment of Renal Lesions With Blood Oxygenation Level-Dependent MRI at 3 T: Preliminary Experience

作者：Min Ji Hye; Kim Chan Kyo^*; Park Byung Kwan; Kim EunJu; Kim Bohyun

来源：American Journal of Roentgenology, 2011, 197(3): W489-W494.

DOI：10.2214/AJR.10.6319

• blood oxygenation level-dependent
• kidney disease
• MRI

OBJECTIVE. The purpose of this article is to prospectively determine the feasibility of using blood oxygenation level-dependent (BOLD) MRI at 3 T in differentiating various renal lesions.
SUBJECTS AND METHODS. Seventy-one patients (mean age, 53.8 years; range, 22-80 years) underwent kidney MRI, including BOLD MRI at 3 T. BOLD MRI was performed using a multiple fast-field echo (FFE) sequence to acquire 20 T2*-weighted images within a single breath-hold. The rate of spin dephasing (R2*) values of solid and benign cystic renal lesions were compared, and the results of four subgroups-simple cysts, renal cell carcinomas (RCCs), hemorrhagic cysts, and angiomyolipomas (AMLs)-were analyzed. The degree of overall imaging quality in BOLD MRI was also assessed.
RESULTS. One hundred three renal lesions were detected in the 71 patients. The mean (+/- SD) R2* values of 45 solid lesions (30.6 +/- 19.4 1/s) were significantly higher than those of 58 benign cystic lesions (4.5 +/- 4.8 1/s; p < 0.001). The mean R2* values of simple cysts, RCCs, hemorrhagic cysts, and AMLs were 1.7 +/- 1.7, 22.6 +/- 12.6, 10.7 +/- 3.7, and 48.0 +/- 25.5 1/s, respectively (p < 0.001). The degree of overall imaging quality in all patients was satisfactory or better.
CONCLUSION. Renal BOLD MRI at 3 T is a feasible technique and may be useful for differentiating various renal lesions.

• 出版日期2011-9