Unprecedented dual reactivity of anhydrous potassium hydroxide in cascade cyclopropannelation/Haller-Bauer-scission/Grob-fragmentation reactions

作者：Krief Alain^*; Kremer Adrian

来源：Tetrahedron Letters, 2010, 51(33): 4306-4309.

DOI：10.1016/j.tetlet.2010.06.007

• Fragmentation
• Cyclopropannelation
• Hydroxide ion
• Wet potassium hydroxide
• Anhydrous potassium hydroxide
• Vinyl cyclopropane carboxylic acid

We report an unprecedented type of reactivity of 'anhydrous potassium hydroxide' ('APH') in which it plays, over a large variety of related educts. sequentially the role of base and nucleophile Some insight into the structure of reactive species as well as comparative reactivity of

• 出版日期2010-8-18