A retrospective review of the dermatologic manifestations of chronic arsenic poisoning in the Philippines

作者:Sy Sheena Maureen T*; Salud Gnilo Charissa M; Yap Silva Claudine; Tababa Erin Jane L
来源:International Journal of Dermatology, 2017, 56(7): 721-725.
DOI:10.1111/ijd.13615

摘要

BackgroundThe Section of Dermatology of the University of the Philippines, Philippine General Hospital, reported a case of chronic arsenic poisoning from a community in Luzon island to the Department of Health resulting in the conduct of two health and environmental assessment missions in December 2014. ObjectiveTo describe the demographic profile and cutaneous manifestations of chronic arsenic poisoning among affected residents in Luzon, Philippines. MethodsA review of the medical records of 116 residents screened during the health assessment missions in December 2014 was conducted. ResultsAmong the 116 residents screened, 81 (70%) had clinically confirmed arsenic keratoses and hyperpigmentation. Among them, 52 were males and 29 were females with age range of 4-82 years. Two cases of squamous cell carcinoma in situ were detected through skin biopsy. High levels of arsenic in the tap water and topsoil supported the occurrence of an epidemic of chronic arsenic poisoning. ConclusionSpecific dermatologic findings of arsenic keratoses and pigmentation were common among the residents screened. Significantly higher occurrence of arsenic keratoses was seen in adults.

  • 出版日期2017-7