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摘要
Nanoparticles that synchronously exhibit fluorescence and magnetism have great potential in biomedical applications. In this study, porous magnetic nanospheres ranging mainly from 300 to 800nm in diameter were prepared by spray-drying an ethanol solution containing an ethyl cellulose (EC) polymer and Fe3O4 nanoparticles, carried out at lower temperatures (e.g. 40 degrees C). The pores in the nanospheres were mainly caused by the addition of the Fe3O4 nanoparticles in the EC precursor. It was found that the more Fe3O4 nanoparticles added into the EC precursor, the greater the number and size of the pores in the nanospheres. Positively charged quantum dots (QDs) could be easily adsorbed onto the surface of these porous magnetic nanospheres through a simple electrostatic interaction. It was also found that the greater the porosity of the nanospheres, the more QDs could be adsorbed. The QD-coated magnetic nanospheres obtained are expected to have good multifunctionality due to the synchronous exhibition of bright fluorescence and superparamagnetism. This is a novel, simple and highly efficient method for preparing magneto-fluorescent nanospheres, which are expected to be of considerable interest to material scientists and biologists.
- 出版日期2013-7-1
- 单位同济大学
