New Eudesmane Sesquiterpenoids from Salvia plebeia R. Br.

作者：Ma, Lie-Feng; Wang, Peng-Fei; Wang, Ji-Dong; Tong, Xiang-Min; Shan, Wei-Guang; Zhang, Hui^*; Zhan, Zha-Jun^*

来源：Chemistry and Biodiversity, 2017, 14(8): e1700127.

DOI：10.1002/cbdv.201700127

• Salvia plebeia R
• Br
• Eudesmane
• Sesquiterpenoids
• Salplebeone

Three new sesquiterpenoids, salplebeones A-C (1-3), were isolated from the ethanol-soluble extract of the aerial part of Salvia plebeia R. Br. Their structures were established by detailed analysis of NMR and MS spectra. Salplebeone A was an eudesmane lactone, while salplebeones B and C were rare eudesmane sesquiterpenoids, containing 12,8-lactam groups. Antiproliferative activities of salplebeones A-C to myeloid leukemia cell lines were evaluated.

• 出版日期2017-8
• 单位浙江工业大学; 浙江省人民医院