Aspergillus nidulans asexual development: making the most of cellular modules

作者：Etxebeste Oier^*; Garzia Aitor; Espeso Eduardo A; Ugalde Unai

来源：Trends in Microbiology, 2010, 18(12): 569-576.

DOI：10.1016/j.tim.2010.09.007

Asexual development in Aspergillus nidulans begins in superficial hyphae as the programmed emergence of successive pseudohyphal modules, collectively known as the conidiophore, and is completed by a layer of specialized cells (phialides) giving rise to chains of aerial spores A discrete number of regulatory factors present in hyphae play different stage-specific roles in pseudohyphal modules, depending on their cellular localization and protein-protein interactions Their multiple roles include the timely activation of a sporulation-specific pathway that governs phialide and spore formation Such functional versatility provides for a new outlook on morphogenetic change and the ways we should study it

• 出版日期2010-12