科研之友
微信
新浪微博
Facebook
分享链接
摘要
More than 85% of American children raised in the 1970s had blood lead (BPb) levels greater than or equal to 10 mug/dL, the level that currently defines childhood Pb poisoning. With exposure and absorption Pb accumulates in bone. Bone Pb release back to blood also occurs, particularly when kinetic rates of bone turnover are elevated. We examined a group of childbearing age, urban African American and Hispanic women to determine whether they had measurable bone Pb and whether bone Pb levels changed during pregnancy. Tibial bone Pb content was assessed sequentially 3 times over 4 months by L-line X-ray fluorescence (LXRF); for pregnant enrollees this occurred during the second and third trimesters and 1-2 months postpartum LXRF is a noninvasive, low-dose radiation technique that measures superficial cortical bone Pb, Other measures included age, years living in New York City, BPb and a home Pb assessment employing KXRF methodology. Of 53 women evaluated 34 were pregnant. Of these 34, 2 had blood Pb levels greater than or equal to 10 mug/dL; 2 had bone Pb levels above the minimum detection limit of the instrumentation at the time of enrollment. A case report is presented in which a declining bone Pb level was accompanied by an increase in BPb concentration. We surmise that the prevalence of elevated bone
- 出版日期2001-2
