Acute presentation of nasal-type natural killer/T-cell lymphoma of the orbit

作者：Qin Wei^*; Yin Zhengqin; Madge Simon N

来源：European Journal of Ophthalmology, 2009, 19(4): 679-682.

DOI：10.1177/112067210901900425

• Natural killer cell
• Lymphoma
• Imaging
• Orbit

PURPOSE. An unusual case of nasal-type natural killer/T-cell lymphoma (NKTL) of the orbit is reported.
Methods. The clinical history, computed tomography, magnetic resonance imaging, and biopsy specimen of a 29-year-old man with a right orbital lymphoma were evaluated.
RESULTS. The patient initially presented with conjunctival injection and had flu-like symptoms before developing right proptosis and reduced vision; imaging showed a diffuse infiltrative process throughout the orbit. Orbital biopsy revealed angiodestruction with prominent necrosis, and angiocentric lymphoma growth and lymphoma cells were positively stained for CD3, CD20, CD45RO, CD56, cytotoxic molecules (granzyme B and T-cell intracellular antigen-1), and Epstein-Barr virus.
CONCLUSIONS. NKTL is rare and may present acutely; the imaging findings presented serve to highlight the radiologic features of the disease. (Eur J Ophthalmol 2009; 19: 679-82)

• 出版日期2009-8
• 单位中国人民解放军陆军军医大学