The Successful Treatment of Refractory Polyarteritis Nodosa Using Infliximab

作者：Matsuo Satoko; Hayashi Keigo; Morimoto Eisaku; Kato Ayako; Sada Ken Ei^*; Watanabe Haruki; Takano Narazaki Mariko; Sunahori Watanabe Katsue; Kawabata Tomoko; Wada Jun

来源：Internal Medicine, 2017, 56(11): 1435-1438.

DOI：10.2169/internalmedicine.56.8235

• infliximab
• polyarteritis nodosa
• rituximab

Polyarteritis nodosa (PAN), characterized by arteritis of medium-sized blood vessels, is usually treated with a combination of glucocorticoids and immunosuppressants; however, some cases are refractory to these treatments. We herein report the case of a man with PAN that was refractory to various immunosuppressive treatments, including cyclophosphamide, methotrexate, and rituximab. After infliximab (IFX) treatment was initiated, his symptoms improved dramatically and remission was maintained. IFX is considered to be an effective alternative treatment for PAN which proves to be refractory to several immunosuppressive treatments.

• 出版日期2017