The trajectory of lung cancer patients in Western Australia - A data linkage study: Still a grim tale

作者：Jiwa Moyez^*; Maujean Eric; Spil**ury Katrina; Threlfal Tim

来源：Lung Cancer, 2010, 70(1): 22-27.

DOI：10.1016/j.lungcan.2010.01.007

• Lung cancer
• Data linkage
• Prognosis
• Surgery
• Radiotherapy
• Symptoms

Objective: To plot the trajectory of lung cancer patients by linking multiple data sources in Western Australia.
Design: Database survey, data linkage and postal survey.
Setting: Western Australia.
Participants: Lung cancer patients registered on the cancer registry database of Western Australia, April 2006 to March 2007.
Main outcome measures: Morbidity, mortality, and medical procedures.
Results: 950 lung cancer patients were registered on the cancer registry database from April 2006 to March 2007. Sixty five percent were male with a mean age at diagnosis of 70 years (SD 11 years). Approximately 30% were from regional and remote areas of Western Australia. 76% reported a history of smoking, with a mean of 41 pack-years per smoker. One in four cases had metastases at diagnosis. 18% of cases from a tertiary hospital received no active treatment. The median time from the first visit to GP with recognized cancer symptoms until consultation with a specialist was 2 weeks. One in five cases presented directly to the hospital Emergency Department. For 16% of all cases, no symptoms were recorded in the hospital administrative records at the time of presentation. Fifty-two percent of patients had chemotherapy, 49% received radiotherapy and 21% had surgery. 13% of treated patients were readmitted to hospital with complications of therapy. Median survival was 33 weeks (95% Cl 30-40).
Conclusion: Data linkage offers limited prospects for exploring the trajectory of patients with lung cancer in Western Australia. The available data indicate that the prognosis of lung cancer remains very poor and that a high proportion of patients are still diagnosed with advanced disease. There is no evidence to suggest that a greater proportion of patients are being offered surgical treatment compared to more than a decade ago. However a greater proportion of cases now receive adjuvant therapies and overall median survival has improved by a matter of weeks.

• 出版日期2010-10