科研之友
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摘要
Stenotrophomonas maltophilia, a gram negative rod, is an important emerging nosocomial agent and primary pathogen in human patients. Treatment has proven to be difficult due to natural resistances against a wide range of common antibiotics. Recently, Albini and co-workers (2009) described an association between chronic respiratory diseases in horses and infections with Stenotrophornonas maltophilia. To our current knowledge, no reports about Stenotrophomonas maltophilia as a causative agent of non - respiratory infections in the horse were published to date. This paper describes two equine cases of bacterial infections where Stenotrophomonos maltophilia could be isolated in pure culture. One horse, a multiparous mare, presented with bacterial cystitis and responded well to a ten day course of antibiotics without relapse. The other horse, a polo pony, was diagnosed with advanced bacterial endocarditis of the pulmonary valve. The large vegetations led to stenosis with concurrent car pulmonale and the horse died within a few hours after admission. The pathological examination confirmed the clinical diagnosis and revealed additional metastatic pneumonia and lung abscesses due to embolisotion. Stenotrophomonos maltophilia was isolated from the large vegetations, while the lung abscesses produced no bacterial growth. Despite a recommendation of tetracyclines and trimethoprim/sulfamethoxazole as drugs of choice against infections with Stenotrophomonas maltophilia, in both of our cases the germ was resistant against these antibiotics, but susceptible to marbofloxacin. In summary in horses Stenotrophomonas maltophilia should be taken into account even as a causative pathogenic agent of multiresistant bacterial infections in horses.
- 出版日期2011-8
