Macular pseudohole development after sustained-release dexamethasone intravitreal implant for macular edema due to central retinal vein occlusion

作者：Di Antonio Luca; Toto Lisa^*; Carpineto Paolo; Mastropasqua Alessandra; De Nicola Chiara; Mastropasqua Leonardo

来源：European Journal of Ophthalmology, 2014, 24(1): 134-137.

DOI：10.5301/ejo.5000317

• En face optical coherence tomography
• Macular pseudohole
• Sustained-release dexamethasone intravitreal implant

Purpose: To report a case of macular pseudohole (MPH) development after sustained-release dexamethasone intravitreal implant for chronic macular edema due to central retinal vein occlusion (CRVO).
Methods: A 70-year-old man with cystoid macular edema (CME) due to CRVO underwent sustained-release dexamethasone intravitreal implant. En face optical coherence tomography (OCT) was performed before and after treatment.
Results: One month after dexamethasone intravitreal implant, best-corrected visual acuity (BCVA) improved from 1.0 to 0.5 logMAR. At 2 months, BCVA decreased from 0.5 to 1.3 logMAR. En face OCT detected the development of MPH due to exacerbation of centripetal vitreomacular transverse tractional forces on the overlying retina.
Conclusions: Macular pseudohole seems to be a complication of intravitreal therapy in patients with coexisting vitreomacular traction. En face OCT gives useful information to understand the mechanism of MPH development after sustained-release dexamethasone intravitreal implant.

• 出版日期2014-2