Steroids Glycosylated with Both D- and L-Arabinoses from the South China Sea Gorgonian Dichotella gemmacea

作者：Jiang Mei; Sun Peng; Tang Hua; Liu Bao Shu; Li Tie Jun; Li Cui; Zhang Wen^*

来源：Journal of Natural Products, 2013, 76(4): 764-768.

DOI：10.1021/np300906b

Three new 19-hydroxy steroidal glycosides, namely, junceellosides E-G (2-4), were isolated together with the known analogue junceelloside C (1) from the South China Sea gorgonian Dichotella gemmacea. The structures of these compounds were elucidated by a combination of detailed spectroscopic analyses, chemical methods, and comparison with reported data. These glycosides are found to have sugar moieties of both beta-L- and beta-D-arabinopyranoses by HPLC analysis of their thiocarbamoylthiazolidine derivatives and those of authentic D- and L-arabinoses, leading to the structure revision of junceelloside C (1). This is the first report of steroidal glycosides from the gorgonian D. gemmacea and the first report of glycosides with beta-L-arabinopyranose from marine sources.

• 出版日期2013-4
• 单位中国人民解放军第二军医大学