A New Scoring Method of the Mini-Mental Status Examination to Screen for Dementia

作者：Choe Jin Yeong; Han Ji Won; Kim Tae Hui; Kim Jeong Lan; Moon Seok Woo; Park Joon Hyuk; Kim Shin Gyeom; Kim Bong Jo; Kwak Kyung Phil; Ryu Seung Ho; Yoon Jong Chul; Lee Dong Young; Lee Dong Woo; Lee Seok Bum; Lee Jung Jae; Jhoo Jin Hyeong; Kim Ki Woong^*

来源：Dementia and Geriatric Cognitive Disorders, 2014, 37(5-6): 347-356.

DOI：10.1159/000357471

• Mini-Mental Status Examination
• Short form score
• Dementia
• Accuracy
• Specificity

Background: Although the Mini-Mental Status Examination (MMSE) is the most widely used screening instrument for dementia, it has several limitations. Methods: We developed and validated a new scoring method of the MMSE, namely the short form of the MMSE (MMSE-S). Results: The MMSE-S was more robust to demographic influences than the MMSE. The influence of education, in particular, was smaller in the MMSE-S compared to the MMSE (p %26lt; 0.01). The diagnostic accuracy of the MMSE-S for very mild to mild dementia was also better than that of the original MMSE (p %26lt; 0.0001). Its specificity, in particular, was higher than that of the original MMSE. In Korea, we could improve the post-test probability for dementia from 46.88 to 64.76% by employing the MMSE-S instead of the MMSE. We also provided optimal cut-off scores for dementia stratified by age, education, and gender, which may further improve the diagnostic accuracy of the MMSE-S for dementia. Conclusion: Due to its good accuracy and brevity, the MMSE-S may contribute to enhancing the cost-effectiveness of and accessibility to dementia screening as well as early diagnosis and treatment of dementia, particularly in low-and middle-income countries.

• 出版日期2014