Acute Lung Injury with Alveolar Hemorrhage Due to a Novel Swine-Origin Influenza A (H1N1) Virus

作者：Yokoyama Toshiki; Tsushima Kenji^*; Ushiki Atsuhito; Kobayashi Nobumitsu; Urushihata Kazuhisa; Koizumi Tomonobu; Kubo Keishi

来源：Internal Medicine, 2010, 49(5): 427-430.

DOI：10.2169/internalmedicine.49.3022

• influenza
• H1N1
• alveolar hemorrhage
• acute lung injury

A 40-year-old woman with no major medical illness except for morbid obesity (BMI 40.7) was admitted to our hospital because of bilateral pneumonia due to a novel swine-origin influenza A (H1N1) virus (S-OIV). Non-invasive ventilation was introduced because of the hypoxemia. The description of bronchoalveolar lavage fluid findings showed an alveolar hemorrhage and neutrophilic inflammation. No evidence of bacterial infection was found. She was treated with oseltamivir and sivelestat sodium, neutrophil elastase inhibitor and thereafter was successfully discharged from the hospital. This case is the first report of a patient with acute lung injury with an alveolar hemorrhage caused by the S-OIV.

• 出版日期2010