Mathematical Modeling of Metabolism and Hemodynamics

作者：Costalat R; Francoise J P^*; Menuel C; Lahutte M; Vallee J N; de Marco G; Chiras J; Guillevin R

来源：Acta Biotheoretica, 2012, 60(1-2): 99-107.

DOI：10.1007/s10441-012-9157-1

• Magnetic resonance spectroscopy
• Multinuclear spectroscopy
• Regional cerebral blood flow
• Differential equation
• Viability
• Slow-fast dynamics

We provide a mathematical study of a model of energy metabolism and hemodynamics of glioma allowing a better understanding of metabolic modifications leading to anaplastic transformation from low grade glioma.This mathematical analysis allows ultimately to unveil the solution to a viability problem which seems quite pertinent for applications to medecine.

• 出版日期2012-6