Multicomponent, solvent-free synthesis of 12-aryl-8,9,10,12-tetrahydrobenzo[a]-xanthen-11-one derivatives catalysed by cyanuric chloride

作者：Zhang, Zhan-Hui^*; Zhang, Peng; Yang, Shu-Hong; Wang, Hong-Juan; Deng, Jia

来源：Proceedings of the Indian Academy of Sciences: Chemical Sciences , 2010, 122(3): 427-432.

DOI：10.1007/s12039-010-0049-0

• Xanthenes
• aldehydes
• 2-naphthol
• multicomponent reactions
• cyanuric chloride
• solvent-free condition

An efficient and direct protocol for the preparation of 12-aryl-8,9,10,12-tetrahydro-benzo[a] xanthen-11-one derivatives employing a three-component one-pot reaction of aryl aldehydes, 2-naphthol and cyclic 1,3-dicarbonyl compounds in the presence of a catalytic amount of cyanuric chloride (2,4,6-trichloro- 1,3,5-triazine, TCT) under solvent-free conditions is described. The desired products are obtained in high yields with short reaction times.

• 出版日期2010-5
• 单位河北师范大学