Abnormal sexuality in Parkinson%26apos;s disease: fact or fancy?

作者：Ferrucci Roberta; Panzeri Marta; Ronconi Lucia; Ardolino Gianluca; Cogiamanian Filippo; Barbieri Sergio; Barone Paolo; Bertolasi Laura; Padovani Alessandro; Priori Alberto

来源：Journal of the Neurological Sciences, 2016, 369: 5-10.

DOI：10.1016/jjns.2016.07.058

• Sexuality
• Sexual function
• Parkinson's disease
• NSF
• IIEF
• FSFI

Purpose: Patients with Parkinson's disease (PD) variably report sexual dysfunctions. We assessed sexuality in PD by comparing sexual function between a large group of patients with idiopathic PD and a group of subjects without PD.
Methods: We recruited 121 patients with mild-to-moderate PD (aged 40-80 years) from four Italian Movement Disorder Clinics and 123 non-Parkinsonian controls (NPC) (aged 40-80 years). Sexual function was assessed with four scales: the Brief Index of Sexual Functioning (BISF-M for men; BISF-W for women), the International Index of Erectile IIEF), and the Female Sexual Function Index (FSFI). Both groups also underwent assessment with the Beck Depression Inventory (BDI) and the Mini Mental State Examination (MMSE), and patients were assessed with the Parkinson's Disease Questionnaire-8 (PDQ-8).
Results: No differences in total score were found between PD and NPC for any sexual function scale (BISF-M, BISFW, IIEF, FSFI: p> 0.05). However, the Orgasm/Pleasure Domain (BISF, D5) was significantly lower in male patients than in controls.
Conclusion: Our findings fail to confirm previous findings that PD is associated with a significant sexual impairment. NPC and patients with PD have comparable sexual function in both sexes. Thus, rather than dismissing sexual dysfunction as a normal parkinsonian symptom, physicians should refer patients to sexual medicine specialists who can investigate and discuss problems fully, diagnose possible comorbidities, and suggest appropriate treatments.

• 出版日期2016-10-15