摘要
Administration of enantiomerically pure beta-adrenergic agonists and antagonists increases their activity and reduces side effects. We report here a small-molecule artificial receptor (SMAR) that, by mimicking the beta-adrenergic receptor, is able to enantioselectively extract commercial beta-adrenergic interacting drugs. The selectivity is justified according to DFT calculations and X-ray diffraction experiments.
- 出版日期2016