A TRIM16-Galactin3 Complex Mediates Autophagy of Damaged Endomembranes

作者:Fraiberg Milana; Elazar Zvulun*
来源:Developmental Cell, 2016, 39(1): 1-2.
DOI:10.1016/j.devcel.2016.09.025

摘要

Selective autophagy, an essential process for maintaining intracellular homeostasis, depends on precise target recognition and local activation. Reporting in Developmental Cell, Chauhan et al. (2016) elegantly demonstrate that interaction between TRIM16 and Galectin3 orchestrates the recruitment of core autophagic factors and activates selective autophagy at the site of damaged endomembranes.

  • 出版日期2016-10-10