NH4I-Mediated Three-Component Coupling Reaction: Metal-Free Synthesis of β-Alkoxy Methyl Sulfides from DMSO, Alcohols, and Styrenes

作者：Gao, Xiaofang; Pan, Xiaojun; Gao, Jian; Jiang, Huanfeng; Yuan, Gaoqing^*; Li, Yingwei

来源：Organic Letters, 2015, 17(4): 1038-1041.

DOI：10.1021/acs.orglett.5b00170

• S BOND
• ALKENES
• OLEFINS
• OXYSULFENYLATION
• DISULFIDES
• AMMONIUM
• SULFONES
• CLEAVAGE
• KINETICS
• HALIDES

A novel synthesis recipe for beta-alkoxy methyl sulfides was developed via NH4-mediated three-component oxysulfenylation reaction of styrenes with DMSO and alcohols. This method features simple operation and readily available starting materials, and it provides an alternative sulfenylating agent generated from DMSO for oxysulfenylation reactions.

• 出版日期2015-2-20
• 单位华南理工大学