Nano-silica sulfuric acid as an efficient catalyst for the synthesis of substituted pyrazoles

作者：Emtiazi Hamideh; Amrollahi Mohammad Ali^*; Mirjalili Bi Bi Fatemeh

来源：Arabian Journal of Chemistry, 2015, 8(6): 793-797.

DOI：10.1016/j.arabjc.2013.06.008

• Trisubstituted pyrazoles
• Nano silica sulfuric acid
• Hydrazines
• 1,3-Diketones

A convenient and direct approach has been developed for the preparation of pyrazole derivatives by condensing 1,3-diketones and hydrazines in the presence of nano-silica sulfuric acid. This thermal solvent-free procedure offers some advantages such as short reaction time, simple work-up, high yields, and reusability of the catalyst.

• 出版日期2015-11