科研之友
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摘要
Paracetamol caused liver damage as evident by significant increase in the activities of aspartate and alanine transferases There were general statistically significant losses in the activities of superoxide dismutase catalase glutathione peroxidase and glutathione transferase and an increase in thiobarbituric acid reactive substances in the liver of paracetamol treated group compared with the control group However treatment with ethanol extract of A flos aquae (EEAFA) was able to counteract these effects Protection offered by silymarin (standard reference drug) seemed relatively greater The results suggest that EEAFA can act as hepatoprotective agent against paracetamol induced toxicity as an antioxidant
- 出版日期2010-11
