A case report: Non-alcoholic Wernicke encephalopathy associated with polyneuropathy

作者：Liang, Hudong; Wu, Lan; Liu, Ling-ling; Han, Jinming; Zhu, Jie; Jin, Tao^*

来源：Journal of International Medical Research, 2017, 45(6): 1794-1801.

DOI：10.1177/0300060517699039

• Polyneuropathy
• Wernicke encephalopathy

We report a rare case of non-alcoholic Wernicke encephalopathy (WE) with polyneuropathy. A 24-year-old woman who had recently served a 4-month prison sentence and underwent a short period of dieting manifested slow response, weakness, language disorder and amnesia. Brain magnetic resonance imaging (MRI) revealed typical lesions of WE. Examination of nerve conduction velocity revealed sensory-motor axonal polyneuropathy. The patient was immediately treated with thiamine. Neurological symptoms were alleviated in a few days and abnormal signals were markedly decreased in a follow-up MRI 1 week later. Polyneuropathy symptoms ameliorated during hospital therapy and significantly improved after 4 months. This case suggests that WE may be associated with polyneuropathy in non-alcoholic patients. Early thiamine treatment in symptomatic patients may improve prognosis.

• 出版日期2017-12
• 单位吉林大学