Assessment of the initial viscoelastic properties of a critical segmental long bone defect reconstructed with impaction bone grafting and intramedullary nailing

作者：Costi John J^*; Stanley Richard M; Ding Boyin; Solomon Lucian B

来源：Medical Engineering & Physics, 2014, 36(1): 39-48.

DOI：10.1016/j.medengphy.2013.09.003

• Bone allograft
• Segmental defect
• Impaction bone grafting
• Biomechanical testing
• Compression stiffness
• Bending stiffness
• Torsion stiffness
• Fixation stability
• Fracture stability
• Tibia
• Sheep
• Phase angle

Introduction: This study compared the initial viscoelastic properties of a segmental tibial defect stabilized with intramedullary nailing and impaction bone grafting to that of a transverse fracture stabilized with intramedullary nailing.
Materials and methods: Seven sheep tibiae were tested in compression (1000 N), bending and torsion (6 Nm) in a six degree-of-freedom hexapod robot. Tests were repeated across three groups: intact tibia (Intact), transverse fracture stabilized by intramedullary nailing (Fracture), and segmental defect stabilized with a nail and impaction bone grafting (Defect). Repeated measures ANOVA on the effect of group on stiffness/phase angle were conducted for each loading direction.
Results: The Intact group was significantly stiffer than the Fracture and Defect groups in bending and torsion (p < 0.022 for both loading directions), and was marginal for the Defect group in compression (p = 0.052). No significant differences were found between the Fracture and Defect groups (p > 0.246 for all loading directions) for stiffness/phase angle. In compression and bending, phase angles were significantly greater for the Fracture and Defect groups compared to Intact (p < 0.025), with no significant differences between groups in torsion (p = 0.13). Sensitivity analyses conducted between the Fracture and Defect group differences found that they were not of clinical significance.
Conclusion: The initial properties of a segmental defect stabilized with intramedullary nailing and impaction bone grafting was not clinically significantly different to that of a transverse fracture stabilized with intramedullary nailing.

• 出版日期2014-1