Novel 1-Aminomethylisatins: Peculiarities of the Synthesis and the Reaction with Tris(diethylamino)phosphine

作者:Bogdanov Andrei V*; Musin Lenar I; Il'in Anton V; Mironov Vladimir F
来源:Journal of Heterocyclic Chemistry, 2014, 51(4): 1027-1030.
DOI:10.1002/jhet.2011

摘要

The Mannich reaction of isatin with different primary and secondary amines and effect of the substituent in aromatic amines on the reaction pathway is studied. The efficient high-yield synthesis of novel isoindigo derivatives by the mild deoxygenation reaction of the corresponding isatins with tris(diethylamino)phosphine is described.

  • 出版日期2014-7