Development of nanofibrillated cellulose coated with gold nanoparticles for measurement of melamine by SERS

作者：Xiong Ziyi; Chen Xiaowei; Liou Polly; Lin Mengshi^*

来源：Cellulose, 2017, 24(7): 2801-2811.

DOI：10.1007/s10570-017-1297-7

• Nanofibrillated cellulose
• Melamine
• Milk
• SERS
• Gold nanoparticles

The objective of this study was to develop nanofibrillated cellulose (NFC)-based substrate for rapid detection of melamine in milk by surface-enhanced Raman spectroscopy (SERS). NFC were served as a highly porous platform to load with gold nanoparticles (AuNPs), which can be used as a flexible SERS substrate with nanoscale roughness to generate strong electromagnetic field in SERS measurement. The NFC/AuNP substrate was characterized by UV-Vis spectroscopy and electron microscopy. Milk samples contaminated by different concentrations of melamine were measured by SERS coupled with NFC/AuNP substrate. The spectral data analysis was conducted by multivariate statistical analysis [i.e. partial least squares (PLS)]. Satisfactory PLS result for quantification of melamine in milk was obtained (R = 0.9464). The detection limit for melamine extracted from liquid milk by SERS is 1 ppm, which meets the World Health Organization's requirement of melamine in liquid milk. These results demonstrate that NFC/AuNP substrate has improved homogeneity and can be used in SERS analysis for food safety applications.

• 出版日期2017-7