A novel and selective synthetic approach for the access of pyrrolo [1,2-a] imidazol-7-one or pyrrol-3-one

作者：Zeng, Hui; Yuan, Pengtao; Wang, Fukai; Xu, Xiaoyong; Shao, Xusheng; Li, Zhong^*

来源：Tetrahedron Letters, 2016, 57(36): 4031-4035.

DOI：10.1016/j.tetlet.2016.07.055

• Dihydropyrroloimidazol-6-ones
• beta-Nitroenamine
• Pyrrolo[1,2-a]imidazol-7-one
• Pyrrol-3-one
• One-pot

A novel and metal-free synthetic method for the formation of pyrrolo[1,2-a]imidazol-7-one or pyrrol-3-one from dihydropyrroloimidazol-6-one through the C-N bond cleavage and formation was achieved. The salient features of this method are operational simplicity, mild reaction conditions, and readily available starting materials.

• 出版日期2016-9-7
• 单位华东理工大学