科研之友
微信
新浪微博
Facebook
分享链接
摘要
An interesting Umpolung strategy to generate beta-carbanion equivalents from a conjugated enal has been developed. The enal group of compounds 7 was chemospecifically converted to a delocalized carbanion by decarboxylation of the in situ formed imine between the enal and 2,2-diphenylglycine (2), which then underwent nucleophilic addition at the beta position of the enal to an intramolecular aldehyde group to give cyclized products 8 in 54-93% yields.
- 出版日期2017-8-1
- 单位上海师范大学
