A rare new cleistanthane diterpene from the pericarp of Trewia nudiflora

作者:Du Zhi Zhi; Shen Yue Mao*
来源:Helvetica Chimica Acta, 2006, 89(11): 2841-2845.
DOI:10.1002/hlca.200690256

摘要

A minor, unprecedented diterpene, 3 beta,17-dihydroxycleistantha-12,15-dien-2-one (1), was isolated from the CHCl3-soluble part of the EtOH extract of the pericarp of Trewia nudiflora. The structure of I was elucidated by means of 1D- and 2D-NMR spectroscopic analyses as well as by HR-MS. Also isolated were two known triterpenes, glutin-5-en-3-ol and olean-18-en-3-one (germanicone), as well as three known sterols, (22E,24R)-5 alpha,8 alpha-epidioxyergosta-6,22-dien-3 beta-ol, (22E,24R)-5 alpha,8 alpha-epidioxyergosta-6,9(11),22-trien-3 beta-ol, and (22E,24R)-6-methoxyergosta-7,22-dien-3,5-diol.