The LiP (Lifestyle in Pregnancy) Study A randomized controlled trial of lifestyle intervention in 360 obese pregnant women

作者：Vinter Christina A^*; Jensen Dorte M; Ovesen Per; Beck Nielsen Henning; Jorgensen Jan S

来源：Diabetes Care, 2011, 34(12): 2502-2507.

DOI：10.2337/dc11-1150

OBJECTIVE-To study the effects of lifestyle intervention on gestational weight gain (GWG) and obstetric outcomes.
RESEARCH DESIGN AND METHODS-The LIP (Lifestyle in Pregnancy) study was a randomized controlled trial in 360 obese women allocated in early pregnancy to lifestyle intervention or control. The intervention program included dietary guidance, free membership in fitness centers, physical training, and personal coaching.
RESULTS-A total of 360 obese pregnant women were included, and 304 (84%) were followed up until delivery. The intervention group had a significantly lower median (range) GWG compared with the control group of 7.0 (4.7-10.6) vs. 8.6 kg (5.7-11.5; P = 0.01). The Institute of Medicine (IOM) recommendations on GWG were exceeded in 35.4% of women in the intervention group compared with 46.6% in the control group (P = 0.058). Overall, the obstetric outcomes between the two groups were not significantly different.
CONCLUSIONS-Lifestyle intervention in pregnancy resulted in limited GWG in obese pregnant women. Overall obstetric outcomes were similar in the two groups. Lifestyle intervention resulted in a higher adherence to the IOM weight gain recommendations; however, a significant number of women still exceeded the upper threshold.

• 出版日期2011-12