Association of Adherence to a Healthy Diet with Cognitive Decline in European and American Older Adults: A Meta-Analysis within the CHANCES Consortium

作者：Berendsen Agnes A M; Kang Jae H; van de Rest Ondine; Jankovic Nicole; Kampman Ellen; Kiefte de Jong Jessica C; Franco Oscar H; Ikram M Arfan; Pikhart Hynek; Nilsson Lena Maria; Brenner Hermann; Boffetta Paolo; Rafnsson Snorri Bjorn; Gustafson Deborah; Kyrozis Andreas; Trichopoulou Antonia; Feskens Edith J M; Grodstein Francine; de Groot Lisette C P G M

来源：Dementia and Geriatric Cognitive Disorders, 2017, 43(3-4): 215-227.

DOI：10.1159/000464269

• Ageing
• Diet
• Nutrition
• CHANCES
• Cognition
• Cohort
• Epidemiology
• Healthy Diet Indicator

Aim: To examine the association between a healthy diet, assessed by the Healthy Diet Indicator (HDI), and cognitive decline in older adults. Methods: Data from 21,837 participants aged >= 55 years from 3 cohorts (Survey in Europe on Nutrition and the Elderly, a Concerted Action [SENECA], Rotterdam Study [RS], Nurses' Health Study [NHS]) were analyzed. HDI scores were based on intakes of saturated fatty acids, polyunsaturated fatty acids, mono-and disaccharides, protein, cholesterol, fruits and vegetables, and fiber. The Telephone Interview for Cognitive Status in NHS and Mini-Mental State Examination in RS and SENECA were used to assess cognitive function from multiple repeated measures. Using multivariable-adjusted, mixed linear regression, mean differences in annual rates of cognitive decline by HDI quintiles were estimated. Results: Multivariable-adjusted differences in rates in the highest versus the lowest HDI quintile were 0.01 (95% CI -0.01, 0.02) in NHS, 0.00 (95% CI -0.02, 0.01) in RS, and 0.00 (95% CI -0.05, 0.05) in SENECA with a pooled estimate of 0.00 (95% CI -0.01, 0.01), I-2 = 0%. Conclusions: A higher HDI score was not related to reduced rates of cognitive decline in European and American older adults.

• 出版日期2017
• 单位河北医科大学